Cover art featuring Kingpin and Spider-Man

1st appearance of The Danvers Family: Joseph, Marie, Joseph Jr.

1st appearance of Sapper

1st appearance of Golden Blade

1st appearance of Arsenal (Alpha), a robot developed by Allied World War II scientists and Howard Stark, Tony's father

Death of Count Nefaria

"Demon in a Bottle" part 5

"Demon in a Bottle" part 7

3rd appearance of Black Cat

Origin of Nightcrawler

First meeting of the new X-Men and Dr. Strange

1st appearance of Margali Szardos, the adoptive mother of Nightcrawler

1st appearance of Stefan Szardos, the adoptive brother of Nightcrawler

1st appearance of Madame Web

[February 2022 - Dakota Johnson cast as Madame Web]

Wedding of Peter Parker and Gwen Stacy in an alternate reality

1st full appearance of Uranos, an Eternal

Origin of the Eternals continued

1st appearance and origin of Hydro-Man

1st full appearance of Sabra, an Israeli mutant with enhanced strength

[September 2022 - confirmed for the Captain America: New World Order film]

1st full team appearance of the Soviet Super-Soldiers: Darkstar, Crimson Dynamo, Ursa Major, Vanguard

1st appearance of Pieter Phobos

2nd appearance of Madame Web

'Doomquest' part one - a two-issue series that established Dr. Doom as a major foe of Iron Man and also one who has many formidable similarities to Tony Stark

Battle of Iron Man vs Dr. Doom

Iconic cover art by John Romita Jr.

1st appearance of Firestar, not in regular continuity

Comic book adapted from the cartoon series that ran from 1981-1986

1st appearance of Captain Marvel, Monica Rambeau later becomes Photon, then Spectrum

"Nothing Can Stop the Juggernaut" part 1

First limited series published by Marvel Comics

1st appearance of Blitzkrieg, able to summon lightning

1st full appearance of the Collective Man, six brothers who can merge into one

1st appearance of Shamrock, a hand-to-hand combatant

1st appearance of Defensor, possessor of a Vibranium suit of armor

1st appearance of Peregrine, utilizes a flight suit in battle

1st appearance of Talisman, an Australian magic user

"Nothing Can Stop the Juggernaut" part 2

$1.25 Canadian price variant

Death of Tarantula

1st appearance of the Hobgoblin, Roderick Kingsley

A complete issue includes the ‘Tattooz' giveaway insert, found between the final page and the back cover. See additional images - be aware that the insert may be there but the tattoos might still be missing

[Feb 2021 - a social media account associated with Sony seemingly teased the transformation of Ned Leeds into the Hobgoblin - view image by tapping cover and swiping / June 2022 - Jacob Batalon reshared a photo holding a Hobgoblin action figure which caused future movie speculation on social media]

1st appearance of Hobgoblin

4-page interior Mark Jewelers advertisement, printed on paper stock and bound into the centerfold

Distributed to stores near military bases or on-site

Approximately only 5% of the print run included these advertisements

$0.75 Canadian price variant

2nd appearance of the Hobgoblin

First battle of Spider-Man vs the Hobgoblin

Origin of Vulture

3rd appearance of the Hobgoblin

1st cameo appearance of Lefty Donovan, becomes the second Hobgoblin in the next issue

1st appearance and death of the second Hobgoblin, Lefty Donovan

1st appearance of Valerie Cooper, a government official for mutant regulatory practices, led to the formation of X-Factor

1st appearance of Leech

Cover art by John Romita Jr. featuring Hobgoblin, Roderick Kingsley

Battle of Colossus versus the Juggernaut

1st appearance of Forge, Daniel Lone Eagle, a mutant with the ability to comprehend and build nearly anything technological

1st appearance of Naze, a Cheyenne mystic and mentor to Forge, later revealed to be the Adversary

Storm is stripped of her powers and doesn't regain them until nearly four years later in Uncanny X-Men #226

1st cameo appearance of the Adversary, a Native American trickster god

1st appearance of Nimrod, an advanced sentinel from an alternate timeline

1st appearance of Firestar in mainstream continuity, previously appeared in the comic book adaptation of the animated series 'Spider-Man and His Amazing Friends'

James Proudstar appears in the classic Thunderbird costume

1st team appearance of Andrea and Andreas Strucker, the twin children of Baron Von Strucker that comprise the terrorist organization Fenris

Later the twins take on the identities of Swordsman (Thunderbolts) and Songbird

The Strucker family was loosely adapted for 'The Gifted' TV show on Fox (2017-19)

[January 2021- a fake commercial in WandaVision advertises a brand of watches named 'Strucker' a nod to Baron Von Strucker that could also hint at an MCU introduction of the Strucker twins]

Controversial issue: in an effort to make a point about the offensiveness of the word 'mutie', Kitty Pryde uses an extremely offensive racial slur, uncensored

1st appearance of Rachel Summers as the second Phoenix

The Brotherhood of Evil Mutants becomes the Freedom Force: Mystique, Blob, Destiny, Spiral, Avalanche and Pyro

'Trial of Magneto'

Magneto becomes headmaster of Xavier's Academy

Andrea and Andreas Von Strucker become Fenris, a terrorist organization

[July 2022 - the X-Men ‘97 teaser depicts Magneto clothed as shown on this cover]

Iconic cover art by John Romita Jr.

First mention of the term Omega when referring to the power class of a mutant

1st cameo team appearance of The Marauders: Arclight, Harpoon, Riptide, Vertigo, Scalphunter and Scrambler

📖 Reading Order: Mutant Massacre Prologue 1

1st appearance of Star Brand, a mechanic who is given a powerful alien artifact

New Universe was an imprint by Marvel that introduced new super-powered characters in a more realistic universe

1st full team appearance of The Marauders: Arclight, Riptide, Vertigo, Harpoon, Scalphunter, Scrambler

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

📖 Reading Order: Mutant Massacre Part 1

Marriage of Peter Parker and Mary Jane Watson

A retrospective of Peter Parker and Mary Jane Watson's relationship, published during the same month as The Amazing Spider-Man #21 - Special Wedding Issue