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1st appearance of Dr. Soranik Natu, a neurosurgeon and the daughter of Sinestro

1st appearance of Isamot Kol, a Lizarkon from Thanagar saved by the Lanterns from execution

DC Vertigo ⋅ 1991
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1st full appearance of Thessaly, a witch

Variant ⋅ DC ⋅ 2019
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Variant cover art by Francesco Mattina

Store exclusive, a virgin variant (no title text) also exists

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1st appearance of Nightshade

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1st appearance of Nehanda, Black Panther circa 1,000 AD

1st appearance of Benhazin, a former king of Wakanda

1st appearance of Negus, a former king of Wakanda

Marvel ⋅ 1976
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Cover art by Gil Kane suspected to have been the uncredited inspiration for Rob Liefeld's New Mutants #87 cover featuring Cable

Marvel ⋅ 2011
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Ultimate Reed Richards' face is disfigured by Johnny Storm which becomes a physical differentiation of the Maker separating him from the mainstream Marvel Universe version of Mr. Fantastic

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1st team appearance and origin of the Ultimate Fantastic Four: Reed Richards, Sue Storm, Johnny Storm, Ben Grimm

First introduced in in Marvel Team-Up #9, a Fantastic Four team made multiple unofficial appearances in the Ultimate Universe (Earth-1610) but it wasn't until this issue that an official continuity began

There is also a lengthy non-continuity sequence involving the Fantastic Four included in Ultimate Spider-Man Special (July 2002)

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1st appearance of the Key, a being obsessed with power and unlocking the secrets of the world

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1st team appearance of Damage Control, a crew that cleans and repairs damage caused during super-powered conflicts

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