TV shows based on comic books that were made for Hulu or optioned by Hulu Comic properties optioned prior to 2019 without an update will not be included on the list

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1st appearance and origin of Lady Bullseye

Hellraiser #1

Epic 1989 Vol. 1
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1st cover only appearance of Pinhead, appears in-story in issue #2

Ongoing series that lasted 20 issues, inspired by characters and events in Clive Barker's Hellraiser

Epic is a defunct imprint of Marvel Comics

Runaways #1

Marvel 2003 Vol. 1
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1st team appearance of the Runaways: Alex Wilder, Karolina Dean aka Lucy in the Sky, Molly Hayes aka Bruiser, Nico Minoru aka Sister Grimm, Chase Stein aka Talkback, Gertrude Yorkes aka Arsenic

1st team appearance of the Pride

[July 2022 - Marvel trademarked the title Runaways: New Era]

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1st appearance of M.O.D.O.K., a Mechanized Organism Designed Only for Killing

1st appearance of Animaniacs in comics

1st appearance of Pinky and the Brain in comics

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1st appearance and origin of Hit Monkey

The Hit Monkey one-shot went on sale one week before Deadpool #19 which is often confused as his first appearance

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Premiere issue of a series created by Brian K. Vaughn about the last man on a female populated Earth

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