November 1961: The Fantastic Four #1 ushered in a new era for Marvel, formerly Atlas Comics. November 1986:  Marvel commemorated the event with the 25th Anniversary frames seen below. Since then, there have been a number of homage covers to commemorate these memorable covers. 

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Marvel 25th Anniversary border

Amazing Spider-Man #601

Marvel 2009 Vol. 1
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Variant cover art by John Romita Jr.

70th anniversary of Marvel Comics character frame

Marvel's Voices: Pride #1

Marvel 2021 Vol. 1
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1st cover appearance of Somnus

Variant cover art by Luciano Vecchio

Cover art inspired by the Marvel 25th Anniversary frames that were first seen on covers in 1986

Moon Knight #4

Marvel 2021 Vol. 9
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Ultimate Comics
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Ms. Marvel #43

Marvel 2009 Vol. 2
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Variant cover art by Sana Takeda

70th anniversary of Marvel Comics character frame

Wolverine: First Class #18

Marvel 2009 Vol. 1
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Variant cover art by Takeshi Miyazawa

70th anniversary of Marvel Comics character frame

Guardians of the Galaxy #17

Marvel 2009 Vol. 2
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Variant cover art by Mike Perkins

70th anniversary of Marvel Comics character frame

Miles Morales: Spider-Man #9

Marvel 2019 Vol. 1
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Variant cover art by Pasqual Ferry

Marvel 80th anniversary frame

Marvels Project, The #1

Marvel 2009 Vol. 1
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Blank sketch variant

70th anniversary of Marvel Comics character frame

Wolverine: Origins #39

Marvel 2009 Vol. 1
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Variant cover art by Herbe Trimpe

70th anniversary of Marvel Comics character frame

Amazing Spider-Man #641

Marvel 2010 Vol. 1
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Variant cover art by John Tyler Christopher

Women of Marvel variant

Invincible Iron Man #16

Marvel 2009 Vol. 2
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1:10
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70th anniversary of Marvel Comics character frame

Moon Knight #2

Marvel 2021 Vol. 9
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Ultimate Comics
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Black Cat #9

Marvel 2021 Vol. 2
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Variant cover art by Art Adams

Store exclusive, anniversary frame border

Beta Ray Bill #1

Marvel 2021 Vol. 1
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Variant cover art by Mike McKone

Store exclusive, anniversary frame border

Wolverine: Weapon X #4

Marvel 2009 Vol. 1
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Amazing Spider-Man #602

Marvel 2009 Vol. 1
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Variant cover art by Patrick Zircher

70th anniversary of Marvel Comics character frame

Daredevil #500

Marvel 2009 Vol. 1
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Variant cover art by Patrick Zircher

70th anniversary of Marvel Comics character frame

Amazing Spider-Man #603

Marvel 2009 Vol. 1
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Variant cover art by Mike Mayhew

70th anniversary of Marvel Comics character frame

Black Panther #7

Marvel 2009 Vol. 5
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Variant cover art by Ken Lashley

70th anniversary of Marvel Comics character frame

Marvel Age #44

Marvel 1986 Vol. 1
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Cover art by Alan Kupperberg & Joe Sinnott featuring Starbrand

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

2nd full appearance of Apocalypse

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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1st appearance of Galactypus, a platypus version of Galactus

1st appearance of Kingpig

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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1st team appearance of the Stunticons

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Cover art by Barry Windsor-Smith featuring Magik

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

Kitty Pryde, speaking at a memorial service uses multiple offensive words related to ethnicity and sexual orientation

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Marriage of Namor and Marrina

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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1st full team appearance of The Marauders: Arclight, Riptide, Vertigo, Harpoon, Scalphunter aka John Greycrow, Scrambler

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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1st appearance of Rick Jones as the Hulk

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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1st appearance of John Walker as Super-Patriot, later becomes U.S. Agent

1st team appearance of The Buckies: Lemar Hoskins, later becomes Battlestar, Hector Lenox and Jerome Johnson, later become Left-Winger and Right-Winger

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Cover art depicting Hordak

Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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Specialty border printed on select covers published in November 1986 celebrating Marvel's 25th Anniversary or more precisely, the 25th year since Fantastic Four #1 was published in November 1961

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