Spider-Man's Arch-Villains

Marvel May 1963

Amazing Spider-Man #2

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$1.6K
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3rd appearance of Spider-Man
1st appearance of Vulture
1st appearance of the Terrible Tinkerer
1st cameo appearance of Mysterio, disguised as the assistant of the Terrible Tinkerer
Spider-Man first references his ability to sense danger as his Spider-Sense tingling
Marvel Jul 1963

Amazing Spider-Man #3

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$1.2K
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$4K
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1st appearance, cover and origin of Dr. Octopus
Debut of the 'Spider's Web' fan letters section
An editing error has Doctor Octopus mistakenly refer to Spider-Man as Super-Man
Marvel Sep 1963

Amazing Spider-Man #4

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$500
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$1.5K
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$5K
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1st appearance and origin of Sandman
1st appearance of Betty Brant, a secretary at the Daily Bugle
Spider-Man refers to himself as 'The Friendly Neighborhood Spider-Man' for the first time
1st cameo appearance of Jessica Jones, a spectator of the Sandman versus Spider-Man fight - this appearance is retconned as revealed in The Amazing Spider-Man #601

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