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1st appearance of Venom, Eddie Parker, an alternate dimension mash-up of Peter and Eddie Brock bonded to a symbiote named Pete

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1st appearance of Flicker, a Symbiote bonded to a host named Lin

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1st appearance of the Venom Horse

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1st full appearance of Black Widow as Widow bonded to her symbiote

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1st appearance of Liz Allan as Misery

1st appearance of Corwin Jones, later becomes Madness

Thor #27

Marvel 2022 Vol. 6
Non-Key
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1st appearance of the spawn of Bedlam symbiote, possessing Darkoth

Earth X #3

Marvel 1999 Vol. 1
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1st cameo appearance of Spiders Man, a reptilian version of Spider-Man

1st full appearance of Venom, May Parker

Amazing Spider-Man #793

Marvel 2018 Vol. 1
Non-Key
1:25
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Variant cover art by Ryan Stegman featuring Spider-Man bonded with Maniac

1st appearance of Blindspot, Sam Chung

1st appearance of Claire Dixon, later bonds to the symbiote Raze

1st cameo appearance of Grant Ward aka Iron Thief in the Agents of S.H.I.E.L.D series

Introduction of the Rascal symbiote, bonds with Normie Osborne

Black Panther #2

Marvel 2018 Vol. 7
2nd Print
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Variant second printing cover art by Daniel Acuna

1st cover appearance of the N'Jadaka symbiote

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1st appearance of Bren Waters, the teenage host of Toxin

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1st appearance of Silence, a Scream/Anti-Venom hybrid symbiote bonded to Andi Benton

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1st appearance of the symbiote that later bonds with Gwen to become Gwenom

1st appearance of Dr. Elsa Brock, the Eddie Brock of Gwen Stacy's reality

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1st team appearance of the Resistance, heroes with symbiotes

The Resistance led by Captain Venom

1st partial team appearance of The Poisons, a race of aliens who devour symbiotes and their hosts

Poisons: Hulk, Doctor Octopus, Spider-Man

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1st appearance of Ngozi, a young Nigerian girl in possession of the Venom symbiote in an alternate reality

The character that appears in Marvel Voices Legacy is not a new symbiote

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1st appearance of the second Captain Universe

1st appearance of Mister E, a being from the Shadowverse

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1st appearance and origin of Lee Price, bonds with the Venom symbiote

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Origin of Gorr the God Butcher

1st cameo appearance of Knull the Symbiote God

Introduction of the All-Light, a spear that is the antithesis of Knull's All-Black Necrosword

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1st cover appearance of Ultimate Venom

1st appearance of the synthetic symbiote in a beaker that later bonds to The Maker

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Dr. Conrad Marcus becomes Venom

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1st appearance of Gwen Stacy as Gwenom

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April Parker becomes Mayhem, a genetic clone of May Parker and a human/symbiote hybrid

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Preview appearance of Bile, a cannibalistic madman with the strength and eating habits of a spider

Bile was presented as a joke in this issue but CBR posts an article about Donny Cates taking an interest in the character even though it seemed the tweet exchange was more conversational without future plans

Character never appeared in a story but bears similar horror attributes as Spiders-Man of Earth 11580: See Spider-Verse button for more

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1st appearance of Carla Unger, a scientist who briefly bonded with the Carnage symbiote

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1st appearance of Marcus the Centaur Werewolf Symbiote Warrior

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1st appearance of Sleeper, the result of Eddie Brock bonding with the infant Symbiote

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Deadpool bonds with Hybrid symbiote

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1st appearance of Patricia Robertson as Scream, formerly She-Venom

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Brief appearance of the yet-to-be named symbiote planet of Klyntar

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1st appearance of Spider-Man's black costume

Cited as being tied with Marvel Team-Up #141 as the first appearance of the black costume, this issue went on sale January 31,1984

Marvel Team-Up #141 went on sale February 14,1984

Cover art inspired by Amazing Fantasy #15

The symbiote costume was designed by a Marvel fan from Illinois named Randy Schueller who was paid $220 by Editor-In-Chief Jim Shooter for the concept

[March 2026 - the evolution of Spider-Man in the Spider-Man (Tom Holland franchise) may be building toward a symbiote bond, based on clues in the latest Spider-Man: Brand New Day trailer]

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1st full appearance of Normie Osborn as Goblin Childe

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1st team appearance and origin of the Exolon, parasites made of living darkness created by Knull

1st team appearance of the Nameless, a group of lost Kree explorers infected by the Exolon

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1st appearance of N'Jadaka, the new Emperor bonded to a symbiote

What The--?! #20

Marvel 1992 Vol. 1
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1st appearance of Pork Grind, a Spider-Ham Universe version of Venom

Symbiote Spider-Man #1

Marvel 2019 Vol. 1
Non-Key
Store Exclusive
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Variant cover art by Jay Anacleto featuring the Carnage Queen, Mary Jane Watson

1st cover appearance of the Carnage Queen

Mighty Avengers #8

Marvel 2008 Vol. 1
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Janet Van Dyne aka Wasp is overtaken by a symbiote virus along with a number of other heroes

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1st appearance of Addy Brock, pilot of the mechanized Ven#m suit

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1st appearance of The Mercury Team, a US task force deployed to hunt down symbiotes equipped with the Life Foundation symbiotes: Phage, Lasher, Agony, Riot

Mercury Team was a Sym-Soldier program that became known as Project Venom

Copies ordered by retailers: 30,378

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1st appearance of Karl Malus as Superior Carnage

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1st team appearance of the Vipers, a female squadron of symbiote assassins led by Venom

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1st full appearance of Phage

1st full appearance of Agony

1st full appearance of Riot

1st full appearance of Lasher

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1st appearance of Kron Stone as Venom 2099

Kron Stone first appears in Punisher 2099 #1

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Origin of Symbiotes

Introduction of the planet Klyntar, named after the Symbiote word for "cage”, comprised of Symbiote mass with Knull's physical body at the center - brief, unnamed appearance of Klyntar in Spider-Man Family #1 (2007)

First mention of the team Agents of the Cosmos

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1st appearance of Gorr, the God Butcher

1st appearance of the Necrosword, the first symbiote created by Knull

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1st appearance of Spider-Carnage, Ben Reilly possessed by Carnage

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1st full appearance of Knull,the creator of the Symbiote alien race

Knull's first cameo appearance is in Thor: God of Thunder #6

The spiral emblem associated with Knull is a reference to Chthulhu mythology

Knull was the first being that existed in nothingness that preceded the creation of the current Marvel Universe

[September 2024 - the latest Venom trailer revealed Knull to be a villain in the film]

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1st appearance and death of Krobaa, an alien symbiote, intergalactic explorer

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1st appearance of Poison, a symbiote fully in control of Peter Parker's body

Cover art inspired by Leonardo da Vinci's Vitruvian Man

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1st appearance of Payback, Mavis Trent, a S.H.I.E.L.D agent with a symbiote nourished by the emotion of happiness

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