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- 1st appearance and origin of Adam Warlock (formerly HIM)
- "Adam" was the name given to him by children, Warlock given by the High Evolutionary
- 1st mention of the Infinity Gauntlet's Soul Gem
- 1st team appearance of Infinity Watch: Adam Warlock, Drax the Destroyer, Moondragon, Gamora, Pip the Troll and Thanos
- Each member was given control of one Infinity Gem