33 Eyes: Curse of the Gesu #3 (1995)

Yakuma's ordinary life ended the day he met Pai, an immortal being with a desperate wish to become human. They've been through a lot together -- some bad, much good, all extraordinary -- and have tried to assimilate it into a normal life. Now Yakuma has come to accept that normalcy is a thing of his past, and so he and Pai prepare to leave Tokyo forever. But before they get out of town, they face the strangest occurrence yet; the appearance of the deadly mythical creature -- the dreaded Gesu!