1st team appearance of the Stepford Cuckoos, a product of Weapon XIV, created from Emma Frost's DNA
1st appearance of Angel Salvadore
1st appearance of Cerebella, a disembodied mutant brain
Artist Ethan Van Sciver hid the word 'sex' in multiple panels throughout the book, many of which were caught by editors but one slipped past which is evident in a protest scene
Captain America revealed to be Weapon I of the Weapon Plus program, more commonly known as the Weapon X program that bonded adamantium to Wolverine's skeleton
