Low $65
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Mid $175
 | 
High $680
  • 1st appearance of Spencer Smythe and the Spider-Slayers
  • 1st cameo appearance of Mary Jane Watson, face is obscured by a tree
  • This issue is cited by some sources as the first appearance of Mary Jane but she does not appear in full until The Amazing Spider-Man #42
Details
Publisher Marvel
Published June 1965
Written By Stan Lee
Illustrated By Steve Ditko