Black Panther: The Most Dangerous Man Alive #524 (2011)

Spider-Island tie-in! First it was American Panther, now it's Six-Armed Panther? The arachnid infection griping Manhattan hits T'Challa, but that doesn't mean he'll stop trying to protect Hell's Kitchen! And when Overdrive breaks into the quarantine zone, your friendly neighborhood Spider-Panther swings into a deadly race across the streets of New York City. What has the Spidey villain stolen that's worth smashing through a hero-protected border, and why is the lethal Lady Bullseye trying to keep him from getting back out?