Spider-Man: Fear Itself #1

The mucky man monster returns to meet the Amazing Spider-Man in a double-sized epic that connects to both Peter Parker's youth and his present-day adventures. In the Florida Everglades, Spider-Man squares off against eight hundred pounds of menace -- the savage, mindless Man-Thing! But after the battle, Spidey finds his own, radiation-altered body chemistry changing radically. To stop his hideous transformation, he'll have to face his own greatest fear!