1st appearance and origin of Ace Spencer, a reformed drug dealer

Death of Jean DeWolff

1st appearance of Sin-Eater, Stanley Carter, a former NYPD detective

The Foreigner first appears disguised as Lieutenant Kris Keating which isn't revealed until The Spectacular Spider-Man #129

3rd cameo of the Foreigner, partially seen

1st full appearance of the Foreigner, a mercenary and the ex-husband of Silver Sable - it is later revealed the Foreigner had impersonated Lieutenant Kris Keating in Spectacular Spider-Man #113 (April 1986) and The Amazing Spider-Man #276 (May 1986)

[March 2022 - Deadline reports Christopher Abbott to play the Foreigner in the Kraven movie]

1st appearance of the intelligent Grey Hulk

Peter David begins writing on The Incredible Hulk title

1st appearance of the fifth Hobgoblin, Jason Macendale, formerly Jack O' Lantern

Team-up of the Grey Hulk and the Leader vs Rick Jones as the Green Hulk

Interior art by Todd McFarlane

Cover art by Steve Geiger, interior art by Todd McFarlane

1st appearance of Mercy, an alien who killed suicidal people who did not have the constitution to take their own lives

Iconic cover art by Todd McFarlane

1st appearance of Rock and Redeemer

Cover art by Todd McFarlane

Cover art by Todd McFarlane

1st appearance of the Hulk personality known as Joe Fixit

1st appearance of Marlo Chandler, wife of Rick Jones who later becomes the second Harpy

1st appearance of Madman

1st appearance of the Riot Squad: Jailbait, Ogress and Hotshot

1st appearance of Atlan, King of Atlantis in his youth

Dale Keown begins artwork on The Incredible Hulk

In the story, 'The Main Event' the Incredible Hulk challenges Hulk Hogan for the use of the name Hulk in what appears to be an unfriendly commentary from Marvel (courtesy of Peter David) aimed at Hogan

After handling Hogan, the Hulk says, “Any other of you clowns want to swipe a name you don’t deserve just to get ahead?”

1st appearance of the Pantheon

Iconic cover art by Jim Lee

Debut of Peter David writing on X-Men

Cover art by Mike Mignola

Hulk becomes the Dark Hulk in the final panel after being possessed by the sorcerer Shanzar

Return of the green-skinned Hulk

1st appearance of Wolverina, a female parody of Wolverine

Classic battle of the Hulk with green skin vs the Hulk with gray skin

1st appearance of Agamemnon, son of Loki and a mortal woman

1st appearance of the Professor Hulk personality (grey/green composite)

1st appearance of Guilt Hulk, a manifestation of Banner's guilt

1st appearance of Delphi, Ajax, Achilles, Hector and Paris of the Pantheon

1st full appearance of Cyber, an invulnerable mutant fused with adamantium

First interior art by Jae Lee, also illustrated the back cover

1st cameo appearance of Cyber aka Silas Burr, later becomes Hornet

Cyber is the villain who gouged out Wolverine's eye leading to the 'Patch' identity

1st new team appearance of X-Factor: Havok, Madrox, Polaris, Strong Guy, Wolfsbane

1st appearance of Speedfreek

1st team appearance of the Nasty Boys: Slab, Ruckus(1st), Ramrod(1st), Hairbag(1st), Gorgeous George(1st), Multiple Man aka James Madrox (duplicate)

Oversized 30th anniversary issue with green foil cover

Origin of the Hulk retold

Cover art inspired by The Incredible Hulk #1 (1962)

1st appearance of Trauma

Battle of Spider-man and Daredevil vs Venom

Issue exclusively obtained through a UNICEF mail-in charity drive

Interior pin-up poster included

1st appearance and origin of Spider-Man 2099

5-page preview in Amazing Spider-Man #365 and an advertisement in Web of Spider-Man #90

Debatable Firsts: many sources cite Amazing Spider-Man #365 the first appearance of Spider-Man 2099 despite text on the cover of the issue that refers to it as a 5-page preview of Spider-Man 2099 #1

X-Cutioner's Song Part Two

Polybagged with a trading card

1st appearance of Maestro, a future version of the Hulk

X-Cutioner's Song Part Six

Polybagged with a trading card

1st cover appearance of Maestro

1st appearance of Random

First indication of a New World Order team led by the Red Skull whose insignia is spotted on an armband

1st appearance of Lazarus

Polybagged

5 pin-up posters

1st appearance of Jennifer D'Angelo, a priest who later becomes Goblin

Hulk battles holographic enemies in a virtual environment, one of which is unmistakably DC's Doomsday, recognizable by his arm and the word 'Doom-' uttered before Hulk knocks him out

Battle of The Incredible Hulk against Venom

Issue exclusively obtained through a UNICEF mail-in charity drive

Foil, embossed cover

1st appearance of Talos the Untamed

[December 2020 - confirmed to appear with Nick Fury in Secret Invasion]

Cameo appearance by Death of the Endless from DC Vertigo's Sandman series

Marriage of Marlo Chandler and Rick Jones

Peter David, the writer, officiates the ceremony

ROM appears in human form

1st cover and second appearance of Talos the Untamed