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1st full appearance of the sister of Reed Richards, cameo in Fantastic Four #35

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Reintroduction of the Witch Queen

1st appearance of Conspiriton, a villain who induces fear with hallucinogens

1st appearance of Sister Supernova

Origin of the Death Ranger and first appearance in original form as Spa'ark

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1st appearance of Gutsen Glory

1st appearance of Eegro the Unbreakable

New Thunderbolts roster: Hawkeye, Spectrum, America Chavez, Power Man, Persuasion, Gutsen Glory, Eegro the Unbreakable

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1st appearance of the Colonialist, a galactic interloper

1st cameo appearance of Buffalo Soldier, a lieutenant of the Colonialist

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1st full appearance of Spider-Woman 2099

Norman Osborn in an alternate reality becomes the Galactic Goblin

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1st appearance of Queen Arrok

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1st appearance of Amber Nightstone, an evil witch born at the same time as Sabrina

1st full appearance of The Revolution

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1st team appearance of the Midnight Suns: Blade, Kushala aka Spirit Rider, Magik, Wolverine, Nico Minoru, and Zoe Laveau

1st appearance of 'apocalyptic new villains'

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1st appearance of Mickey Mxyzptlk, son of Mr. Mxyzptlk

1st appearance and origin of Boy Thunder, Superman's earliest unknown sidekick

Legion of X #5

Marvel 2022 Vol. 1
Non-Key
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1st full appearance of Vox Ignis aka Voice of Fire, a Ghost Rider/Banshee hybrid

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1st appearance of Spintress, a Spider-Princess

1st appearance of Bishop Octopus and Queen Mysteria

1st full cover appearance of Sun-Spider, partially seen on Spider-Verse #6

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1st appearance of Sparrow

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1st team appearance of the Dark Seekers

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1st appearance of Chimera

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1st appearance of Trick and Treat, two impish magical creatures

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1st appearance of Web-Weaver, the first gay alternate universe Spider-Man

1st appearance of Hunter-Spider

1st appearance of a Spider character created by Phil Lord and Christopher Miller, directors of Into The Spider-Verse

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1st appearance of Monolith, the ruler of a society built for Hulks, by Hulks

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Premiere issue of a new Batman Incorporated team led by Ghost-Maker

1st appearance of Black Mist, a member of Batman Incorporated

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1st appearance of Oliviah Zeveron, a Jedi Knight

1st appearance of Vildar Mac, a Jedi

1st appearance of Matthea Cathley, a Jedi Padawan

1st appearance of Tey Sirrek

1st appearance of Sunshine

1st appearance of Tarna Miak

1st appearance of Elris Florent

Phase II of The High Republic, set 150 years before the first volume

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1st full appearance of Sleeper Agent, the Sleeper symbiote with Hank, a new host introduced in Extreme Carnage: Alpha

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1st appearance of Exhaust

1st team appearance of the Shadow Hunters, an F.B.I. splinter agency led by Talia Warroad

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1st appearance of Ronin in comic books, introduced in Star Wars: Visions 'The Duel' episode

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1st appearance of Omega-Bam-Man, an intergalactic pro wrestler

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First mention of the Thirteen: Beth Ross, Molly Pitcher, Ladybug, Judy Garrick, Quiz Kid, Cherry Bomb, The Harlequin's Son, John Henry Jr., Salem the Witch Girl, Golden Age Aquaman, Golden Age Red Lantern, Golden Age Mister Miracle, Golden Age Legionnaire

1st appearance of Cleopatra Pak as Nostalgia

Moon Knight #16

Marvel 2022 Vol. 9
Non-Key
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1st appearance of Lady Yulan, an assassin

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1st appearance of Runaway, a defender of slaves operating in the 19th century

Prequel to the Gotham Knights game slated for release on the same day as this issue goes on-sale

Issue includes redeemable code to unlock the Batcycle in the Gotham Knights game - a special item will be unlocked if codes from all six issues are redeemed

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1st appearance of Mistress Vile, formerly Rita Repulsa

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1st team appearance of the Atelier: Valentine Vuong, Horned Emperor, Last Bite, Ms. Ginko, Mirror, Rahvona, Aster, Drop, Alcaudon

1st appearance of Renesmee aka Princess, a Carnage hybrid prior to maturation

1st appearance of Doombreaker

80-page one-shot celebrating the 30th anniversary of the Death of Superman

Four new stories by the original creative team behind the event

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1st cameo appearance of Phantom One

1st cameo appearance of Fissure, an electricity wielder

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1st cameo team appearance of the Thirteen: Betsy Ross, Cherry Bomb, Ladybug, John Henry Jr., Mister Miracle, Molly Pritcher, Quiz Kid, Salem the Witch Girl, the Boom aka Judy Garrick - daughter of the Golden Age Flash

1st appearance of the Stranger

Biographies of Aquaman, Betsy Ross and Molly Pitcher, Cherry Bomb, Harlequin's Son, John Henry Jr., The Boom, Ladybug, Legionnaire, Mister Miracle, Quiz Kid, Salem The Witch Girl, Red Lantern

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1st team appearance of the Path of the Open Hand, an extremist missionary order

1st team appearance of the Twinkle Sisters

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1st appearance of Gold Goblin

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1st full appearance of Dyxl aka Night-Mite, a fifth-dimensional imp, previously appeared as Ric Grayson in Nightwing #97

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1st full appearance of Red Canary

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2nd cameo appearance of Iden Versio and Inferno Squad

1st appearance of Ajax Sigma, an extremely dangerous droid

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1st appearance of Moriah Mensa

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1st appearance of Hallow's Eve

1st appearance of Fadeaway, a cloaked villain with the ability to teleport

1st cameo appearance of Yellow Beetle

Cameo of pink, green and purple beetles’ spacecrafts

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1st appearance and death of Ruby Sokov, daughter of Red Lantern

1st full appearance and death of Harlequin's Son

1st cameo appearance of Red Lantern, previously featured in a biography in The New Golden Age #1 but not in-story

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1st appearance of Jul Tambor, a pirate

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1st full appearance of Therm Scissorpunch

1st appearance of Quiet Shan

1st appearance of Coromont Vizzle

1st appearance of Alak, leader of the Dank Graks

1st appearance of Inspector Raf

1st appearance of Arkik Von

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1st appearance of Carella, the first love of Thanos

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1st appearance of Min-Jae, a childhood friend of Taegukgi who becomes an enemy

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1st appearance of Burg

1st appearance of Jib Dodger

1st appearance of Migs Mayfeld

1st appearance of Xi'an and Qin

1st appearance of Trapper Wolf

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1st appearance of Hinge

1st cameo team appearance of the Council of Light: Amanda Waller, Peacewrecker (1st), Bright (1st), Bloodsport, Peacemaker

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