Debut of Agatha Harkness younger design

1st appearance of Dormammu, ruler of the Dark Dimension

1st appearance of Clea, future wife of Doctor Strange, unnamed

Doctor Strange first uses the phrase 'By The Hoary Hosts of Hoggoth

1st team appearance of the Goddesses of Thunder, Thor's future granddaughters: Atli, Ellisiv and Frigg

1st full appearance of Riri Williams, suits up in prototype armor

[December 2020 - Dominique Thorne will be introduced as Riri in Wakanda Forever before starring in her own Disney+ series]

1st team appearance of the Inhumans, a race created by the Kree: Triton, Karnak, Lockjaw, Gorgon, Medusa, Crystal and Black Bolt

1st cameo appearance of Black Bolt

1st appearance of Crystal, ability to manipulate the elements

1st appearance of Karnak, a skilled fighter and advisor to Black Bolt

1st appearance of Triton

1st appearance of Moon Girl, Lunella Lafayette

[September 2019 - animated series in the works for Disney+]

1st appearance of Quake, Daisy Johnson

[August 2020/February 2021 - Quake expected to appear in Secret Invasion / May 2022- a Twitter comment by Simu Liu (Shang-Chi) directed toward to the actress who portrayed Quake in Agents of S.H.I.E.L.D. hints that she will reprise the role in the MCU]

1st appearance of Tigra, formerly Cat

1st appearance of Bobbi Morse as Mockingbird

Hidden Message: interior panel of a vehicle in an airport parking lot with a vanity plate that reads FUQU

[December 2021 - speculation that Hawkeye's wife in the Disney+ show will be revealed to be Mockingbird]

1st appearance and origin of the Wasp

1st team appearance and origin of the Fantastic Four: Mr. Fantastic, Invisible Woman, Human Torch, The Thing

1st appearance of Mole Man

1st appearance of Tricephalous

Landmark issue that launched the Marvel Age of comics

💰 In April 2022, a 9.2 sold for $1.5 million

[SDCC 2022 - Phase 6 will open with the Fantastic Four film]

1st team appearance of the Frightful Four: Madame Medusa, Paste-Pot Pete, Sandman, Wizard

1st appearance of Medusa

1st appearance of Jubilee, a Chinese-American teenager with the ability to emit fireworks from her fingers

1st appearance of Black Widow, Yelena Belova

It is disputed whether this is a full or cameo appearance

CGC labels this issue "1st appearance of the new Black Widow (Yelena Belova, face not shown)"

[September 2022 - confirmed for the Thunderbolts movie]

1st appearance and origin of the real Monet St. Croix

Origin of Claudette and Nicole St. Croix

Origin of Emplate

Patsy Walker becomes Hellcat after finding the first Cat's superhero suit

1st full appearance of Kamala Khan as Ms. Marvel in-story

1st appearance of Bruno Carrelli

1st appearance of Tanalth the Pursuer

1st appearance of Dawn Greenwood, an ally of the Silver Surfer

Copies ordered by retailers: 32,929

1st full appearance of Jane Foster as Thor throughout the story, previously appeared in final page cameos

Variant cover art by Chris Bachalo

1st cover appearance of Gwenpool, does not appear in story

1st team appearance of the Young Avengers: Kate Bishop, Patriot, Asgardian aka Wiccan, Hulkling, and Iron Lad, who is later revealed to be a young variant of Kang

1st appearance of Barbara Norris as Valkyrie

Valkyrie joins the Defenders

1st full appearance of Angela in the Marvel Universe, later revealed to be Thor's sister

Marvel acquired the rights to Angela after nearly a decade of litigation between Todd McFarlane and Neil Gaiman in which Gaiman was victorious

Angela makes her first cameo in the Marvel Universe in Age of Ultron #10

1st full appearance of Silk, a Korean-American girl who was bitten by the same radioactive spider as Peter Parker

[April 2021 - filming for the Amazon TV series begins August 2021]

📖 Spider-Verse Reading Order: read The Amazing Spider-Man #4 and #5

1st appearance and origin of Spider-Woman, Jessica Drew

1st appearance and death of Otto Vermis

[June 2021 - Issa Rae will voice Spider-Woman in Into The Spider-Verse 2]

1st appearance of Squirrel Girl

1st team appearance of the Brotherhood of Evil Mutants led by Magneto

1st appearance of Scarlet Witch

1st appearance of Quicksilver

1st appearance Mastermind, later becomes Jason Wyngarde

1st appearance of Toad

2nd appearance of Magneto

Although the Scarlet Witch's costume is colored green on the cover, it is red in the story

1st appearance of Shuri, T'Challa's sister and future Black Panther

1st appearance of S'yan, the uncle of T'Challa who held the throne after T'Chaka's assassination

[August 2021 - an inside source reveals to Key Collector Comics that Shuri will be the Black Panther in the MCU]

1st appearance of Sif as she is depicted going forward which is visually different than Sif from Journey Into Mystery #102 (1964)

1st appearance of the Lurking Unknown, a Fear Lord

🥈 Runner-Up: New High [Previous High]

9.0 sold for $450 [$232 in 2015] +94%

1st appearance of Rogue

1st cover appearance of Mystique

1st and only appearance of a girl named Maddy Pryor should not be confused with Madelyne Pryor aka the Goblin Queen

1st appearance of Silver Sable

1st team appearance of the Wild Pack

[March 2022 - speculation Silver Sable will be introduced in Kraven and have a tweaked origin, hailing from Russia with a possible family gang war featuring the Kravinoff vs Sablinova]

First mention of S.W.O.R.D., Sentient Worlds Observation and Response Department, a division of S.H.I.E.L.D.

1st full appearance of Abigail Brand

[April 2021 - speculation that Abigail Brand will be introduced in Secret Invasion]

1st cameo appearance of the White Tiger, Ava Ayala

1st appearance of Domino, previously seen in New Mutants #98 impersonated by Copycat

Origin of Cable

1st appearance and origin of Betsy Braddock in U.S. comics, renamed Psylocke by Mojo

1st appearance of Meggan in U.S. comics

1st appearance and origin of Elektra

First solo written work on Daredevil by Frank Miller - previous co-writer credit first occurred in issue #165

Elektra misspelled 'Elecktra' on the cover

1st team appearance of New Mutants: Cannonball (1st), Psyche (1st), Wolfsbane (1st), Sunspot (1st), Karma

Psyche aka Dani Moonstar later becomes Mirage

1st appearance of the White Rook, a member of the Hellfire Club

1st appearance and origin of She-Hulk, the cousin of Bruce Banner

1st appearance of the new X-Men: Storm (1st), Nightcrawler (1st), Colossus (1st), Thunderbird (1st), Wolverine (3rd)

Many resources label this the 2nd full appearance of Wolverine and The Incredible Hulk #182 a second cameo

1st appearance of Illyana Rasputin as a child, later becomes Magik

Introduction of Krakoa, the Living Island

First use of the sound effect 'snikt' associated with Wolverine's claws

1st appearance of Elsa Bloodstone, daughter and successor of the famous monster hunter, Ulysses Bloodstone

[September 2022 - Laura Donnelly (The Nevers) to portray Elsa Bloodstone in Werewolf By Night]

1st appearance of Nosferatu in the Marvel Universe

Debut of new powers, Jean Grey is reborn as the Phoenix

Ten years later this moment would be further developed where the Phoenix is an actual cosmic entity of vast power that copied Grey’s physical form while placing her body in a cocoon to heal from her injuries

1st full appearance of Black Tom Cassidy

The Dark Phoenix Saga Part 1

1st appearance of Kitty Pryde

1st appearance of Emma Frost, the White Queen

1st cameo team appearance of The Hellfire Club, in shadows

1st appearance of Nebula

[September 2021 - Gunn claims the roles of Nebula and Mantis are considerable in Guardians of the Galaxy Vol. 3]

1st appearance of Echo, a highly-skilled martial artist who is also deaf

1st appearance of Gamora

2nd appearance of Pip the Troll

3rd appearance of Magus

Debut of new Adam Warlock costume

1st appearance of Jessica Jones

[May 2022 - Ritter tweeted a picture of her and actor Mike Colter with initials of Jessica Jones and Luke Cage plus the hashtags #marvel and #bigtease / rumored to appear in She-Hulk]

1st appearance of Misty Knight, the first black female Marvel hero without superpowers

1st appearance of the Black Cat

[November 2021 - a Black Cat Easter Egg in the Morbius trailer glimpsed on a newspaper that reads 'Black Cat: Friend or Foe?']

1st appearance of X-23, Laura Kinney

Laura Kinney debuted in the animated series X-Men: Evolution (2003)

1st appearance of Carol Danvers as Ms. Marvel

Carol first appears without powers in Marvel Super-Heroes #13 and gains powers in Captain Marvel #18

1st appearance of Captain Marvel, Monica Rambeau later becomes Photon, then Spectrum