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Many Firsts
Featuring Key Issues that introduce more than 5 characters that had, or still have, a continued presence in comics
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- 1st appearance of Ares, Greek god of war, in Marvel continuity
- [April 2021 - speculation that Ares will appear in Thor Love & Thunder and/or on a team]
- 1st appearance of Hermes (Mercury), messenger god
- 1st appearance of Hera, the wife of Zeus
- 1st appearance of Dionysius, god of wine
- 1st cameo appearance of Artemis (Diana), goddess of hunters
- 1st cameo appearance of Hephaestus (Vulcan), weapons-maker of the gods
- 1st appearance of Harokin, a deceased Asgardian adversary to Thor
- 1st appearance of Tana Nile, a Rigellian colonizer in disguise
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- 1st cameo team appearance of The Nine AKA the Midnight Sons: Ghost Rider, Johnny Blaze, Morbius, Blade, Hannibal King, Frank Drake, Sam Buchanan, Victoria Montesi, Louise Hastings
- 1st appearance of the Caretaker
- 1st appearance of Lilith
- 1st appearance of Meatmarket, offspring of Lilith
- [July 2021 - reports that Marvel registered the LLC, Richmond Street Productions for a streaming series leading speculators to believe that it is a reference to the location of the cemetery where Dan Ketch was resurrected as the Ghost Rider]
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- 1st appearance of Bleez
- 1st appearance of Dex-Starr
- 1st appearance of Zilius Zox and other Red Lanterns
- 1st appearance of Saint Walker, Blue Lantern
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- Infinite Destinies part three
- 1st full team appearance of Tiger Division: The General, Luna Snow, Mr. Enigma, Gun-R II, Auntie Ante, White Fox
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- 1st team appearance of the Secret Warriors: Nick Fury, Phobos, Slingshot, Quake, Stonewall, Hellfire and Druid
- 1st appearance of Stonewall, son of the Absorbing Man
- 1st appearance of Druid, son of Doctor Druid
- 1st appearance of Hellfire, descendant of the Phantom Rider
- 1st appearance of Yo-Yo Rodriguez AKA Slingshot
- Cover art inspired by Avengers #16
- [May 2020 - Secret Warriors team is rumored to appear in the MCU]
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- 1st team appearance of New Mutants: Cannonball (1st), Psyche (1st), Wolfsbane (1st), Sunspot (1st), Karma
- Psyche aka Dani Moonstar later becomes Mirage
- 1st appearance of the White Rook, a member of the Hellfire Club
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- 1st appearance of Emily Bright, a girl who has been aware of her magical powers since birth
- 1st appearance of Doyle Dormammu, the illegitimate son of Dormammu
- 1st appearance of Shaylee Moonpeddle
- 1st appearance of German Aguilar
- 1st appearance of Zoe Laveau, Calvin Morse and Dessy
- The Strange Academy preview was featured in four issues that went on sale January 29th, 2020: Thor #2, Ravencroft #1, Doctor Strange #2, Avengers #30
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- 1st full team appearance of the Starjammers: Corsair, Ch'od, Hepzibah, Astra and Raza
- Debut of Wolverine's new "Fang" costume
- 1st team appearance of the Shi'ar Imperial Guard
- 1st appearance of the M'Krann Crystal
- 1st appearance of Gladiator, leader of the Imperial Guard
- 1st appearance of D'Ken Neramani
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- 1st team appearance of the Young Avengers: Kate Bishop, Patriot, Iron Lad, Asgardian, Hulkling
- Iron Lad revealed to be a variant of Kang
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- 1st appearance of Komodo, a girl who experimented with Dr. Connors' Lizard serum
- 1st appearance of Trauma, a shapeshifter who can sense what people fear
- 1st appearance of Hardball
- 1st appearance of Cloud 9
- 1st appearance of Tactigon, an Omega Level alien weapon
- 1st appearance of The Gauntlet, drill instructor for The Initiative
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- 1st appearance of Death Locket AKA Rebecca Ryker, a teenage version of Deathlok
- 1st appearance of Kid Briton, an alternate reality version of Captain Briton
- 1st appearance of Cullen Bloodstone, brother of Elsa
- 1st appearance of Anachronism, a boy whose soul had been merged with the spirit of a Celtic warlord
- 1st appearance of Nara, an Atlantean
- 1st appearance of Apex, a bio-engineered superhuman
- Death of Mettle
- [October 2021 - Cullen Bloodstone will team-up with Elsa in January's Death of Doctor Strange: Bloodstone one-shot]
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- 1st team appearance of the new Agents of Atlas, a superhero team of Asian descent: Shang Chi, Jimmy Woo, Amadeus Cho, Crescent, Io, Luna Snow, Aero, Silk, Sword Master and Wave
- 1st appearance of Luna Snow
- 1st appearance of Crescent & Io
- 1st appearance of Aero
- 1st appearance of Wave, a female Filipino superhero
- 1st cover appearance of Sword Master, not in the story
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- 1st appearance of Hazmat, a woman confined to a hazmat suit who exudes radiation and other deadly substances
- 1st appearance of Mettle, a skinless, armored mutant
- 1st appearance of Striker, fame-obsessed mutant
- 1st appearance of Veil, a young woman with the ability to transform into a gaseous state
- 1st appearance of Finesse, a polymath with powers similar to Taskmaster who is suspected of being her father