Super Key

Featuring issues that have multiple instances of significance 

Marvel Jan 1980

Uncanny X-Men #129

Low
$25
Mid
$80
High
$280
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The Dark Phoenix Saga Part 1
1st appearance of Kitty Pryde
1st appearance of Emma Frost, the White Queen
1st cameo team appearance of The Hellfire Club, in shadows
Marvel Jul 1977

Star Wars #1

Low
$30
Mid
$90
High
$300
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Issues #1 - #6 are an adaptation of 'Star Wars: A New Hope'
1st appearance of Darth Vader
1st appearance of Luke Skywalker
1st appearance of Princess Leia
1st appearance of C-3PO and R2-D2
1st appearance of Grand Moff Tarkin
1st appearance of Beru and Owen Lars
1st appearance of General Tagge
Introduction of Stormtroopers
1st cover appearance of Obi Wan Kenobi and Han Solo (not in story)
📖 Reading Order: read Star Wars (1977) #1 - #6, then Princess Leia #1
Low
$50
Mid
$150
High
$525
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1st appearance of Annihilus, ruler of the Negative Zone
1st appearance of Franklin Richards, as an unnamed infant, considered by Marvel to be the most powerful mutant in the Marvel Universe
[November 2024 - it is rumored Marvel is looking to cast a child in the role of Franklin Richards who will play the character through various ages in future projects]
Introduction of the Cosmic Control Rod, a weapon used by Annihilus that manipulates matter
[December 2024 - Annihilus rumored to be the villain for the Nova TV series]
Marvel Mar 1964

Uncanny X-Men #4

Low
$400
Mid
$1.3K
High
$4.5K
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1st team appearance of the Brotherhood of Evil Mutants led by Magneto
1st appearance of Scarlet Witch
1st appearance of Quicksilver
1st appearance Mastermind, later becomes Jason Wyngarde
1st appearance of Toad
2nd appearance of Magneto
Although the Scarlet Witch's costume is colored green on the cover, it is red in the story
First interaction between Charles Xavier and Magneto, though their origins have since been retconned to have them meet earlier in their lives
Marvel Sep 1963

Uncanny X-Men #1

Low
$6.2K
Mid
$14K
High
$85K
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1st team appearance of the X-Men: Cyclops, Jean Grey aka Marvel Girl, Iceman, Angel, Beast, Professor X
1st appearance of Magneto
Homo Superior concept, coined by Magneto to describe humans born with special abilities introduced in this issue
[June 2026 - there is widespread speculation that Sadie Sink's character in Spider-Man: Brand New Day could be Jean Grey]
Low
$950
Mid
$4.7K
High
$14K
View on eBay
1st appearance of Loki, the Norse god of mischief
1st appearance of Balder, half-brother of Thor
1st appearance of Heimdall, guardian of Bifrost
1st appearance of Tyr, the Norse god of war
1st cameo appearance of Odin, the All-Father, seen from behind
3rd appearance of Thor
Marvel Feb 1973

Iron Man #55

Low
$135
Mid
$480
High
$1.4K
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1st appearance of Thanos, an Eternal from Titan born with the Deviants gene
1st cameo appearance of Eros aka Starfox, brother of Thanos
1st appearance of Kronos, Grandfather of Thanos
1st appearance of Mentor, father of Thanos
1st appearance of Drax the Destroyer, created by Kronus to kill Thanos
1st appearance of the Blood Brothers
Marvel Dec 1965

Fantastic Four #45

Low
$110
Mid
$380
High
$1.5K
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1st team appearance of the Inhumans, a race created by the Kree: Triton, Karnak, Lockjaw, Gorgon, Medusa, Crystal and Black Bolt
1st cameo appearance of Black Bolt
1st appearance of Crystal, ability to manipulate the elements
1st appearance of Karnak, a skilled fighter and advisor to Black Bolt
1st appearance of Triton
Marvel May 1975

Giant-Size X-Men #1

Low
$350
Mid
$1.1K
High
$3.4K
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1st appearance of the new X-Men: Storm (1st), Nightcrawler (1st), Colossus (1st), Thunderbird (1st), Wolverine (3rd)
Many resources label this the 2nd full appearance of Wolverine and The Incredible Hulk #182 a second cameo
1st appearance of Illyana Rasputin as a child, later becomes Magik
Introduction of Krakoa, the Living Island
First use of the sound effect 'snikt' associated with Wolverine's claws
Low
$410
Mid
$1.6K
High
$6.3K
View on eBay
1st team appearance of the Sinister Six: Doctor Octopus, Kraven, Vulture, Electro, Mysterio, Sandman
3rd appearance of Kraven, Vulture, Electro, Mysterio and Sandman
Reprinted in Marvel Tales #150
Character profiles of Dr. Doom, the Lizard and others
Additional pages explain how Spider-Man's powers and gadgetry work
Marvel Nov 1964

Strange Tales #126

Low
$60
Mid
$120
High
$600
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1st appearance of Dormammu, ruler of the Dark Dimension
1st appearance of Clea, future wife of Doctor Strange, unnamed
Doctor Strange first uses the phrase 'By The Hoary Hosts of Hoggoth
[March 2025 - Charlize Theron rumored to reprise the role of Clea in Avengers: Doomsday]
Marvel Jul 1963

Strange Tales #110

Low
$1.7K
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$8.6K
High
$27K
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1st appearance of Doctor Strange
1st appearance of the Ancient One, former Sorcerer Supreme
1st appearance of Wong, Doctor Strange's assistant
1st cameo appearance of Nightmare, multiple panels, named but obscured by shadows
Marvel Aug 1966

Fantastic Four #53

Low
$25
Mid
$85
High
$250
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1st appearance and origin of Klaw
2nd appearance and origin of the Black Panther
1st appearance of T'Chaka, Black Panther's father
First mention of Wakandan Vibranium metal

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